MEMSuniverse » high throughput screening http://www.memsuniverse.com A Passion for Creativity & Innovation Tue, 23 Oct 2012 21:57:22 +0000 en-US hourly 1 http://wordpress.org/?v=3.4.2 Lab on a Tube http://www.memsuniverse.com/microfluidics/lab-on-a-tube.html http://www.memsuniverse.com/microfluidics/lab-on-a-tube.html#comments Fri, 29 Jan 2010 22:17:02 +0000 admin http://www.memsuniverse.com/?p=2210 This video shows droplet libraries which have been generated in capillary tubing using miniature droplet generators. The droplets are encapsulated in silicone oil. Each droplet is chemically isolated from the others and from the walls of the tubing. Trains of droplets in a ‘spool format’ can serve as miniature chemical libraries for high throughput screening.

Duration : 0:0:8


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]]> http://www.memsuniverse.com/microfluidics/lab-on-a-tube.html/feed 0 Microfluidic Encapsulation of Cells in Alginate Capsules for High Throughput Screening http://www.memsuniverse.com/microfluidics/microfluidic-encapsulation-of-cells-in-alginate-capsules-for-high-throughput-screening.html http://www.memsuniverse.com/microfluidics/microfluidic-encapsulation-of-cells-in-alginate-capsules-for-high-throughput-screening.html#comments Thu, 28 Jan 2010 11:26:44 +0000 admin http://www.memsuniverse.com/?p=2205 Encapsulation of eukaryotic cells in alginate using commercially available microtubing. Liquid alginate droplets with encapsulated cells enter from the left. A crosslinking agent (barium chloride, stained with green dye for visualization) enters from the top. Hydrodynamic interactions in the T-junction adds a fixed amount of crosslinking agent to each droplet. Throughputs of up to 20 droplets/second can be achieved.

Ref: V. Trivedi, E.S. Ereifej, A. Doshi, P. Sehgal, P.J. VandeVord, and A.S. Basu, “Microfluidic Encapsulation of Cells in Alginate Capsules for High Throughput Screening,” Proc. IEEE Engineering in Medicine and Biology Conference (EMBC), Sept. 2009, Minneapolis, MN.

Duration : 0:0:15


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