All Entries Tagged With: "high throughput screening"
Lab on a Tube
This video shows droplet libraries which have been generated in capillary tubing using miniature droplet generators. The droplets are encapsulated in silicone oil. Each droplet is chemically isolated from the others and from the walls of the tubing. Trains of droplets in a ‘spool format’ can serve as miniature chemical libraries for high throughput screening. [...]
Microfluidic Encapsulation of Cells in Alginate Capsules for High Throughput Screening
Encapsulation of eukaryotic cells in alginate using commercially available microtubing. Liquid alginate droplets with encapsulated cells enter from the left. A crosslinking agent (barium chloride, stained with green dye for visualization) enters from the top. Hydrodynamic interactions in the T-junction adds a fixed amount of crosslinking agent to each droplet. Throughputs of up to 20 [...]