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U type 1 hole for trapping cells

Using 3T3 cells as a model system, the motion of each individual cell was calculated using a one-way coupled Lagrangian method. The cell was assumed to be a solid sphere, and interactions with other cells were only considered when a cell sedimented in the trap. The ordinary differential equations were solved along the cell trajectory […]

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cell trapping microfluidic device 2

cell loading experiment Experimental loading of PDMS microfluidic array devices with 3T3 cells. Validation of the predictive value of modeling, using 3T3 cells flowed through microfluidic devices containing U-type sieves under the simulation flow parameters, showed excellent agreement between experiment and simulation with respect to cell number per trap and the uniformity of cell distribution […]

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flat type seive for trapping cells

The “flat-type sieve” consists of an array of nine sieves arranged in a symmetric diamond-shaped pattern. Under simulated conditions, sieves closer to the chamber entrances captured cells well for both geometries, while the downstream sieves remained empty. related article: Building a Better Cell Trap: Applying Lagrangian Modeling to the Design of Microfluidic Devices for Cell […]

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Self-Assembling Nanoliter Containers

Nanotechnology, the new science of extreme miniaturization, is a rapidly growing field in engineering. On this size scale, it is extremely difficult and expensive to fabricate analogs of macroscale engineering, such as grippers. Drawing inspiration from biological fabrication in nature, engineers are seeking to self-assemble structures from the bottom up. This manufacturing paradigm has been […]

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cellTRAY Manager Brightfield Scan

A brightfield scan of the cellTRAY using the cellTRAY Manager. Duration : 0:0:29

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Beads in cellTRAY Fluidics System

Fluorescent beads in a microfluidics cellTRAY show “pulsed mode” flow patterns in the cellTRAY Fluidics System CT-2000F by Nanopoint, Inc. More at www.nanopointimaging.com Duration : 0:0:30

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MFDEP cell loading device proof-of-concept

Proof-of-concept of a MEMS device that I designed for my PhD dissertation, at the University of Maryland. Cells are loaded inside a micro-cell cage using dielectrophoresis. The active cancellation of the parasitic traps is necesary, thus becoming the use of multiple frequencies (MFDEP). This is the first machine of its kind, and it is very […]

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Respirocytes: An Artificial Red Blood Cell Replacement

Animation of a respirocyte (an artificial red blood cell) being injected into the bloodstream. We created the animation for the PBS / Devillier Donegan production “Beyond Human.” It has gone on to win the IMM Computational Nanotechnology Prize (Simulation), has appeared in lectures by AI pioneer Ray Kurzweil and nanotechnology pioneers Robert Freitas, David Forrest […]

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Carbon nanotubes (fuel cell catalyst support)

Carbon nanotubes used as catalyst support for fuel cell and hydrogen generation research. After being suspended in a surfactant solution, the carbon nanotubes precipitated when acetone was added. Duration : 0:0:27

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IC microfludic system apparatus- MIT-Harvard CCNE

Integrated Circuit / Microfludic Apparatus built by Tom Hunt Thanks to the MIT-Harvard Center for Cancer Nanotechnology Excellence Duration : 0:0:14

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