MEMSuniverse » cell culture http://www.memsuniverse.com A Passion for Creativity & Innovation Tue, 23 Oct 2012 21:57:22 +0000 en-US hourly 1 http://wordpress.org/?v=3.4.2 Microfluidic Encapsulation of Cells in Alginate Capsules for High Throughput Screening http://www.memsuniverse.com/microfluidics/microfluidic-encapsulation-of-cells-in-alginate-capsules-for-high-throughput-screening.html http://www.memsuniverse.com/microfluidics/microfluidic-encapsulation-of-cells-in-alginate-capsules-for-high-throughput-screening.html#comments Thu, 28 Jan 2010 11:26:44 +0000 admin http://www.memsuniverse.com/?p=2205 Encapsulation of eukaryotic cells in alginate using commercially available microtubing. Liquid alginate droplets with encapsulated cells enter from the left. A crosslinking agent (barium chloride, stained with green dye for visualization) enters from the top. Hydrodynamic interactions in the T-junction adds a fixed amount of crosslinking agent to each droplet. Throughputs of up to 20 droplets/second can be achieved.

Ref: V. Trivedi, E.S. Ereifej, A. Doshi, P. Sehgal, P.J. VandeVord, and A.S. Basu, “Microfluidic Encapsulation of Cells in Alginate Capsules for High Throughput Screening,” Proc. IEEE Engineering in Medicine and Biology Conference (EMBC), Sept. 2009, Minneapolis, MN.

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