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c type sieve

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“C-shaped sieve” shows pronounced aggregation of the cells in the
downstream section of the trap. Large cell aggregates are particularly
unfavorable for microscale cell culture, as they can quickly exhaust
the local nutrients and reduce oxygenation efficiency, stressing the
culture to the point of cell death by necrosis or apoptosis.

related article:
a Better Cell Trap: Applying Lagrangian Modeling to the Design of
Microfluidic Devices for Cell Biology, Min-Cheol Kim, Zhanhui Wang,
Raymond H. W. Lam and Todd Thorsen, Journal of Applied Physics, 103
(2008) 044701.

Filed Under: Bio-MEMS


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