Micro-Electro-Mechanical-Systems (MEMS) » Bio-MEMS

Topology optimization of fluids with the lattice Boltzmann method

admin — Wed, 19 Oct 2011 16:22:09 +0000

Topology Optimization using a GCMMA optimization algorithm and the lattice Boltzmann method to find the optimal material layout for a micro-mixer. Two miscible (Red and blue) fluids enter a channel and should be mixed at the outlet. The evolution of the channel design is displayed on top with green being solid material and white being fluid. The streamlines are overlayed for convenience. The bottom plot shows the mixing profile of the design.
Re=30
Schmidt Number = 4
144×48 mesh

Dave Makhija
University of Colorado at Boulder

Duration : 0:0:26

Pacman Meets CFD in Microfluidic device

admin — Wed, 12 Jan 2011 08:35:55 +0000

This pacman-like animation demonstrates a conceptual microfluidic device in which fluid is
flowing through a series of interconnected channels. When the fluid reaches a
corner in the channel it experiences an impulsive force which drives it out of
the corner. The fluid is wetting relative to the channel surface so surface tension
pulls the droplet down against the surface. Viscosity damps the motion until
a droplet reaches another corner where it is accelerated again.
Courtesy Terrabyte.

Duration : 0:0:41

JetXpert with Nozzle Plate Visualization

admin — Wed, 03 Feb 2010 22:18:04 +0000

The JetXpert system (drop in flight analysis system) is now available with an add-on for nozzle plate visualization. This option has two cameras and two light sources. The face plate wetting module can save images and movies like the JetXpert system.

Duration : 0:0:17

DC motor Peristaltic pump USB control

admin — Mon, 01 Feb 2010 04:11:04 +0000

This is a demonstration of a dual brushed DC motor peristaltic pump control. This configuration can be used in microfluidics, fluidic mixing in industrial and other commercial settings. This compact controller is fully controlled via the USB.

Duration : 0:5:7

E.coli Swimming In Microfluidic Channel Under Laminar Flow

admin — Sun, 31 Jan 2010 03:35:01 +0000

University of Vermont’s Dr. Jane Hill’s Lab of the Engineering Department – animation on a section of research conducted by members of the lab. Animation by Katie Medrek. September 27, 2009.

Duration : 0:0:35

Lab on a Tube

admin — Fri, 29 Jan 2010 22:17:02 +0000

This video shows droplet libraries which have been generated in capillary tubing using miniature droplet generators. The droplets are encapsulated in silicone oil. Each droplet is chemically isolated from the others and from the walls of the tubing. Trains of droplets in a ‘spool format’ can serve as miniature chemical libraries for high throughput screening.

Duration : 0:0:8

Microfluidic Encapsulation of Cells in Alginate Capsules for High Throughput Screening

admin — Thu, 28 Jan 2010 11:26:44 +0000

Encapsulation of eukaryotic cells in alginate using commercially available microtubing. Liquid alginate droplets with encapsulated cells enter from the left. A crosslinking agent (barium chloride, stained with green dye for visualization) enters from the top. Hydrodynamic interactions in the T-junction adds a fixed amount of crosslinking agent to each droplet. Throughputs of up to 20 droplets/second can be achieved.

Ref: V. Trivedi, E.S. Ereifej, A. Doshi, P. Sehgal, P.J. VandeVord, and A.S. Basu, “Microfluidic Encapsulation of Cells in Alginate Capsules for High Throughput Screening,” Proc. IEEE Engineering in Medicine and Biology Conference (EMBC), Sept. 2009, Minneapolis, MN.

Duration : 0:0:15

BioFlux System for Live Cell Assays Under Controlled Shear Flow (Fluxion Biosciences)

admin — Wed, 06 Jan 2010 01:56:45 +0000

BioFlux provides a fully integrated solution for running biologically relevant cellular assays under shear flow. The system utilizes Fluxion’s Well Plate Microfluidics™ (WPM) to provide high content results from a convenient well-plate format. Precise control over shear flow enables a wide variety of cellular and microbiology applications which call for vascular emulation, mechanical stress, compound/buffer exchange and high content analysis.

BioFlux enables a wide variety of cell-based assays in the fields of immunology, vascular biology, microbiology, cancer research, stem cells, and more. Many of these applications benefit from the ability to create a physiologically-relevant shear flow profile, such as platelet adhesion, cell adhesion, rolling velocity, transmigration and stem cell differentiation. Other applications can benefit from the ability to introduce compounds in a time-resolved and well-controlled manner, such as wound healing, pharmacology and neurite-outgrowth assays.

Duration : 0:9:23

Bacteria turn tiny gears

admin — Wed, 23 Dec 2009 13:53:42 +0000

Swarms of bacteria turn two 380-micron long gears, opening the possibility of building hybrid biological machines at the microscopic scale. Read more at Wired: http://www.wired.com/wiredscience/2009/12/bacterial-micro-machine/#more-15684 or Scientific American: http://www.scientificamerican.com/article.cfm?id=brownian-motion-bacteria

Courtesy Igor Aronson.

Duration : 0:0:21

Lipid bilayer formation

admin — Thu, 18 Jun 2009 17:43:13 +0000

Shows the deposition of liposomes on to the surface of an optical chip and their subsequent rupture and merger to form a lipid bilayer. Protein molecules then embed and float in the surface of the bilayer. This is an excerpt from a video that iemedia solutions (http://www.iemedia.co.uk) produced for the Scientific Instrumentation Division of the Farfield Group (http://www.farfield-group.com) to illustrate the measurement capabilities of their Dual Polarisation Interferometry technology.

Duration : 0:0:38